Dossier
clinicaltrials
trial early
A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)
Key claim: This extension study aims to collect long-term safety and efficacy data for bomedemstat in participants with ET and PV who are tolerating and benefiting from the drug in prior trials.
Abstract
The primary purpose of the study is to transition participants into an extension study to collect long-term safety and efficacy data. The study will include participants who are safely tolerating bomedemstat, receiving clinical benefit from its use in estimation of the investigator, and have shown the following criteria:
- Participants from the IMG-7289-202/MK-3543-005 (NCT05223920) study must have received at least 6 months of treatment with bomedemstat;
- Essential thrombocythemia (ET) and polycythemia vera (PV) participants from studies other than IMG-7289-202/MK-3543-005 must have achieved confirmed hematologic remission.
No hypothesis testing will be conducted in this study.
Why this matters
Pending synthesis.