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Dossier clinicaltrials trial early 04-aug-2026

Study to Evaluate Safety, Pharmacokinetic and Pharmacodynamic Dose Escalation and Expansion Study of PXS-5505 in Patients With Primary, Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis

Key claim: PXS-5505 is being studied in an open-label phase 1/2a dose-escalation and expansion trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics in primary, post-PV, and post-ET myelofibrosis.

Abstract

This study will be an open-label phase 1/2a study to evaluate the safety and tolerability of PXS-5505 in patients with primary, postpolycythemia vera (PV) or post-essential thrombocythemia (ET) myelofibrosis.

Why this matters

PXS-5505 is being studied in an open-label phase 1/2a dose-escalation and expansion trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics in primary, post-PV, and post-ET myelofibrosis.

Source

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Briefing card

Study to Evaluate Safety, Pharmacokinetic and Pharmacodynamic Dose Escalation and Expansion Study of PXS-5505 in Patients With Primary, Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis
Stage: trial early · clinicaltrials · 04-aug-2026

PXS-5505 is being studied in an open-label phase 1/2a dose-escalation and expansion trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics in primary, post-PV, and post-ET myelofibrosis.

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External: nct:NCT04676529

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