MPN Watch

Mentioned 1× · first seen 28-apr-2026 · last seen 28-apr-2026

PMD-026 (RSK1 inhibitor)

Current understanding

To be populated as evidence accumulates.

Evidence log

  • 2026-04-21 — Therapeutic RSK1 Targeting in Myelofibrosis: Phase Ib dose-escalation trial (3+3 design with dose expansion n=6) of oral PMD-026, a first-in-class RSK1 inhibitor, is underway in myelofibrosis to identify RP2D; no efficacy or safety data reported yet. (novelty: 4)

Open questions

Related

Contributing findings

clinicaltrials trial early
Therapeutic RSK1 Targeting in Myelofibrosis
21-apr-2026 novelty 4 per-area 5 introduces

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build build 612 · 69ce4cf-dirty · 2026-11-11