iCasp9-transduced allodepleted T cells (CASPALLO)
Current understanding
To be populated as evidence accumulates.
Evidence log
- 2026-07-01 — CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene: CASPALLO (early-phase trial): allodepleted donor T cells transduced with inducible caspase-9 suicide gene allow selective elimination via AP1903 dimerizer, enabling higher post-transplant T-cell doses to accelerate immune reconstitution while providing on-demand GvHD control. (novelty: 4)
Open questions
Related
Contributing findings
CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene
01-jul-2026
novelty 4
per-area 4
introduces