Curcumin (turmeric)

Current understanding

Polyphenol with anti-inflammatory and possible JAK-STAT modulatory effects in preclinical work. Used in some integrative protocols; clinical evidence in MPN limited.

Evidence log

• 2026-03-27 — Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms: cross-connection with curcumin-supplement: The C3 complex/Bioperine formulation under phase II evaluation is the specific clinical-grade preparation of the broader curcumin/turmeric agent; trial results will inform evidence for the general curcumin page. (novelty: 3)

Open questions

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