Fludarabine + Busulfan conditioning regimen
Current understanding
To be populated as evidence accumulates.
Evidence log
- 2026-08-23 — Sequential High-Dose Ruxolitinib and Low-Dose Splenic Irradiation for Pretransplant Management of Splenomegaly Before Allogeneic Hematopoietic Cell Transplantation With Fludarabine/Busulfan-Based Conditioning in Myelofibrosis.: Retrospective MF series reports encouraging engraftment and early survival when Flu/Bu conditioning is preceded by sequential high-dose ruxolitinib + low-dose splenic irradiation for splenomegaly debulking. (novelty: 3)
Open questions
Related
Contributing findings
Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia
27-aug-2026
novelty 2
per-area 1
mentions
Sequential High-Dose Ruxolitinib and Low-Dose Splenic Irradiation for Pretransplant Management of Splenomegaly Before Allogeneic Hematopoietic Cell Transplantation With Fludarabine/Busulfan-Based Conditioning in Myelofibrosis.
23-aug-2026
novelty 3
per-area 2
strengthens